Gelsolin Amyloidogenesis Is Effectively Modulated by Curcumin and Emetine Conjugated PLGA Nanoparticles

Small molecule based therapeutic intervention of amyloids has been limited by their low solubility and poor pharmacokinetic characteristics. We report here, the use of water soluble poly lactic-co-glycolic acid (PLGA)-encapsulated curcumin and emetine nanoparticles (Cm-NPs and Em-NPs, respectively),...

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Detalles Bibliográficos
Autores principales: Srivastava, Ankit, Arya, Prabha, Goel, Surbhi, Kundu, Bishwajit, Mishra, Prashant, Fnu, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440822/
https://www.ncbi.nlm.nih.gov/pubmed/25996685
http://dx.doi.org/10.1371/journal.pone.0127011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440822/
https://www.ncbi.nlm.nih.gov/pubmed/25996685
http://dx.doi.org/10.1371/journal.pone.0127011

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