A critical role for hemolysin in Vibrio fluvialis-induced IL-1β secretion mediated by the NLRP3 inflammasome in macrophages

Vibrio fluvialis causes human diarrhea, but the pathogenesis is not well-studied. We hypothesized that V. fluvialis-secreted hemolysin (VFH) may induce IL-1β secretion through the activation of the NLRP3 inflammasome and contribute to the pathogenicity of V. fluvialis. To examine this possibility, w...

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Detalles Bibliográficos
Autores principales: Song, Liqiong, Huang, Yuanming, Zhao, Meng, Wang, Zhihao, Wang, Shujing, Sun, Hui, Kan, Biao, Meng, Guangxun, Liang, Weili, Ren, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440915/
https://www.ncbi.nlm.nih.gov/pubmed/26052324
http://dx.doi.org/10.3389/fmicb.2015.00510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440915/
https://www.ncbi.nlm.nih.gov/pubmed/26052324
http://dx.doi.org/10.3389/fmicb.2015.00510

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