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Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

Glatiramer Acetate (GA) has provided safe and effective treatment for multiple sclerosis (MS) patients for two decades. It acts as an antigen, yet the precise mechanism of action remains to be fully elucidated, and no validated pharmacokinetic or pharmacodynamic biomarkers exist. In order to better...

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Detalles Bibliográficos
Autores principales: Kolitz, Sarah, Hasson, Tal, Towfic, Fadi, Funt, Jason M., Bakshi, Shlomo, Fowler, Kevin D., Laifenfeld, Daphna, Grinspan, Augusto, Artyomov, Maxim N., Birnberg, Tal, Schwartz, Rivka, Komlosh, Arthur, Hayardeny, Liat, Ladkani, David, Hayden, Michael R., Zeskind, Benjamin, Grossman, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441120/
https://www.ncbi.nlm.nih.gov/pubmed/25998228
http://dx.doi.org/10.1038/srep10191