Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration

Minocycline is a broad-spectrum tetracycline antibiotic. A number of preclinical studies have shown that minocycline exhibits neuroprotective effects in various animal models of neurological diseases. However, it remained unknown whether minocycline is effective to prevent neuron loss. To systematic...

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Detalles Bibliográficos
Autores principales: Cheng, Shanshan, Hou, Jinxing, Zhang, Chen, Xu, Congyu, Wang, Long, Zou, Xiaoxia, Yu, Huahong, Shi, Yun, Yin, Zhenyu, Chen, Guiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441131/
https://www.ncbi.nlm.nih.gov/pubmed/26000566
http://dx.doi.org/10.1038/srep10535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441131/
https://www.ncbi.nlm.nih.gov/pubmed/26000566
http://dx.doi.org/10.1038/srep10535

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