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Biosynthesis and regulation of terpenoid indole alkaloids in Catharanthus roseus

Catharanthus roseus produces a wide range of terpenoid indole alkaloids (TIA). Many of them, such as vinblastine and vincristine, have significant bioactivity. They are valuable chemotherapy drugs used in combination with other drugs to treat lymphoma and leukemia. The TIA biosynthetic pathway has b...

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Detalles Bibliográficos
Autores principales: Zhu, Jianhua, Wang, Mingxuan, Wen, Wei, Yu, Rongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441158/
https://www.ncbi.nlm.nih.gov/pubmed/26009689
http://dx.doi.org/10.4103/0973-7847.156323