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Stereochemical Assignment of the Protein–Protein Interaction Inhibitor JBIR-22 by Total Synthesis**
Recent reports have highlighted the biological activity associated with a subfamily of the tetramic acid class of natural products. Despite the fact that members of this subfamily act as protein–protein interaction inhibitors that are of relevance to proteasome assembly, no synthetic work has been r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441253/ https://www.ncbi.nlm.nih.gov/pubmed/25650886 http://dx.doi.org/10.1002/anie.201411141 |