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Stereochemical Assignment of the Protein–Protein Interaction Inhibitor JBIR-22 by Total Synthesis**

Recent reports have highlighted the biological activity associated with a subfamily of the tetramic acid class of natural products. Despite the fact that members of this subfamily act as protein–protein interaction inhibitors that are of relevance to proteasome assembly, no synthetic work has been r...

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Detalles Bibliográficos
Autores principales: Healy, Alan R, Izumikawa, Miho, Slawin, Alexandra M Z, Shin-ya, Kazuo, Westwood, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441253/
https://www.ncbi.nlm.nih.gov/pubmed/25650886
http://dx.doi.org/10.1002/anie.201411141