Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn’s disease patients

Previous studies have highlighted the role of genetic predispositions in disease, and several genes had been identified as important in Crohn’s disease (CD). However, many of these genes are likely rare and not associated with susceptibility in Chinese CD patients. We found 294 shared identical vari...

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Detalles Bibliográficos
Autores principales: Xiao, Chuan-Xing, Xiao, Jing-Jing, Xu, Hong-Zhi, Wang, Huan-Huan, Chen, Xu, Liu, Yuan-Sheng, Li, Ping, Shi, Ying, Nie, Yong-Zhan, Li, Shao, Wu, Kai-Chun, Liu, Zhan-Ju, Ren, Jian-Lin, Guleng, Bayasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441321/
https://www.ncbi.nlm.nih.gov/pubmed/26000985
http://dx.doi.org/10.1038/srep10514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441321/
https://www.ncbi.nlm.nih.gov/pubmed/26000985
http://dx.doi.org/10.1038/srep10514

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