TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements

BACKGROUND: TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown. We now hypothesized that cytokine secretion from TREK-1-deficient AECs was regulated...

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Detalles Bibliográficos
Autores principales: Schwingshackl, Andreas, Roan, Esra, Teng, Bin, Waters, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441361/
https://www.ncbi.nlm.nih.gov/pubmed/26001192
http://dx.doi.org/10.1371/journal.pone.0126781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441361/
https://www.ncbi.nlm.nih.gov/pubmed/26001192
http://dx.doi.org/10.1371/journal.pone.0126781

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