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Tumor Necrosis Factor-α-Induced Ototoxicity in Mouse Cochlear Organotypic Culture

Tumor necrosis factor (TNF)-α is a cytokine involved in acute inflammatory phase reactions, and is the primary upstream mediator in the cochlear inflammatory response. Treatment of the organ of Corti with TNF-α can induce hair cell damage. However, the resulting morphological changes have not been s...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Wang, Guo-Peng, Xie, Jing, Guo, Jing-Ying, Gong, Shu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441368/
https://www.ncbi.nlm.nih.gov/pubmed/26000970
http://dx.doi.org/10.1371/journal.pone.0127703