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Zinc Protoporphyrin Suppresses β-Catenin Protein Expression in Human Cancer Cells: The Potential Involvement of Lysosome-Mediated Degradation

Zinc protoporphyrin (ZnPP) has been found to have anticancer activity both in vitro and in vivo. We have recently demonstrated that ZnPP diminishes β-catenin protein expression in cancer cells. The present study examined the cellular mechanisms that mediate ZnPP’s suppression of β-catenin expression...

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Detalles Bibliográficos
Autores principales: Wang, Shuai, Hannafon, Bethany N., Lind, Stuart E., Ding, Wei-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441374/
https://www.ncbi.nlm.nih.gov/pubmed/26000787
http://dx.doi.org/10.1371/journal.pone.0127413