Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila

Intragenic microRNAs (miRNAs), located mostly in the introns of protein-coding genes, are often co-expressed with their host mRNAs. However, their functional interaction in development is largely unknown. Here we show that in Drosophila, miR-92a and miR-92b are embedded in the intron and 3’UTR of ji...

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Detalles Bibliográficos
Autores principales: Yuva-Aydemir, Yeliz, Xu, Xia-Lian, Aydemir, Ozkan, Gascon, Eduardo, Sayin, Serkan, Zhou, Wenke, Hong, Yang, Gao, Fen-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441384/
https://www.ncbi.nlm.nih.gov/pubmed/26000445
http://dx.doi.org/10.1371/journal.pgen.1005264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441384/
https://www.ncbi.nlm.nih.gov/pubmed/26000445
http://dx.doi.org/10.1371/journal.pgen.1005264

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