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Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation

In some esophageal cancer patients, radiotherapy may not prevent distant metastasis thus resulting in poor survival. The underlying mechanism of metastasis in these patients is not well established. In this study, we have demonstrated that ionizing radiation may induce epithelial-mesenchymal transit...

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Detalles Bibliográficos
Autores principales: He, Enhui, Pan, Fei, Li, Guangchao, Li, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441389/
https://www.ncbi.nlm.nih.gov/pubmed/26000878
http://dx.doi.org/10.1371/journal.pone.0126149