The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis

Leishmania spp. are trypanosomatid parasites that replicate intracellularly in macrophages, causing serious human morbidity and mortality throughout the world. Trypanosomatid protozoa cannot synthesize heme, so must acquire this essential cofactor from their environment. Earlier studies identified L...

Descripción completa

Detalles Bibliográficos
Autores principales: Renberg, Rebecca L., Yuan, Xiaojing, Samuel, Tamika K., Miguel, Danilo C., Hamza, Iqbal, Andrews, Norma W., Flannery, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441390/
https://www.ncbi.nlm.nih.gov/pubmed/26001191
http://dx.doi.org/10.1371/journal.pntd.0003804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441390/
https://www.ncbi.nlm.nih.gov/pubmed/26001191
http://dx.doi.org/10.1371/journal.pntd.0003804

Ejemplares similares