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Improving 3D Genome Reconstructions Using Orthologous and Functional Constraints

The study of the 3D architecture of chromosomes has been advancing rapidly in recent years. While a number of methods for 3D reconstruction of genomic models based on Hi-C data were proposed, most of the analyses in the field have been performed on different 3D representation forms (such as graphs)....

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Detalles Bibliográficos
Autores principales: Diament, Alon, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441392/
https://www.ncbi.nlm.nih.gov/pubmed/26000633
http://dx.doi.org/10.1371/journal.pcbi.1004298