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Improving 3D Genome Reconstructions Using Orthologous and Functional Constraints
The study of the 3D architecture of chromosomes has been advancing rapidly in recent years. While a number of methods for 3D reconstruction of genomic models based on Hi-C data were proposed, most of the analyses in the field have been performed on different 3D representation forms (such as graphs)....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441392/ https://www.ncbi.nlm.nih.gov/pubmed/26000633 http://dx.doi.org/10.1371/journal.pcbi.1004298 |