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The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling

Pressure overload induces stress-induced signaling pathways and a coordinated transcriptional response that begets concentric cardiac hypertrophy. Although concentric hypertrophy initially attenuates wall stress and maintains cardiac function, continued stress can result in maladaptive cardiac remod...

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Detalles Bibliográficos
Autores principales: Stein, Adam B., Goonewardena, Sascha N., Jones, Thomas A., Prusick, Parker J., Bazzi, Ahmad A., Belyavskaya, Jane M., McCoskey, Makayla M., Dandar, Rachel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441468/
https://www.ncbi.nlm.nih.gov/pubmed/26001054
http://dx.doi.org/10.1371/journal.pone.0127839