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The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling
Pressure overload induces stress-induced signaling pathways and a coordinated transcriptional response that begets concentric cardiac hypertrophy. Although concentric hypertrophy initially attenuates wall stress and maintains cardiac function, continued stress can result in maladaptive cardiac remod...
Autores principales: | Stein, Adam B., Goonewardena, Sascha N., Jones, Thomas A., Prusick, Parker J., Bazzi, Ahmad A., Belyavskaya, Jane M., McCoskey, Makayla M., Dandar, Rachel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441468/ https://www.ncbi.nlm.nih.gov/pubmed/26001054 http://dx.doi.org/10.1371/journal.pone.0127839 |
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