Beyond Two-Stage Models for Lung Carcinogenesis in the Mayak Workers: Implications for Plutonium Risk

Mechanistic multi-stage models are used to analyze lung-cancer mortality after Plutonium exposure in the Mayak-workers cohort, with follow-up until 2008. Besides the established two-stage model with clonal expansion, models with three mutation stages as well as a model with two distinct pathways to...

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Detalles Bibliográficos
Autores principales: Zöllner, Sascha, Sokolnikov, Mikhail E., Eidemüller, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441484/
https://www.ncbi.nlm.nih.gov/pubmed/26000637
http://dx.doi.org/10.1371/journal.pone.0126238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441484/
https://www.ncbi.nlm.nih.gov/pubmed/26000637
http://dx.doi.org/10.1371/journal.pone.0126238

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