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Activation of Salmonella Typhi-Specific Regulatory T Cells in Typhoid Disease in a Wild-Type S. Typhi Challenge Model

Salmonella Typhi (S. Typhi), the causative agent of typhoid fever, causes significant morbidity and mortality worldwide. Currently available vaccines are moderately efficacious, and identification of immunological responses associated with protection or disease will facilitate the development of imp...

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Detalles Bibliográficos
Autores principales: McArthur, Monica A., Fresnay, Stephanie, Magder, Laurence S., Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Dougan, Gordon, Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441490/
https://www.ncbi.nlm.nih.gov/pubmed/26001081
http://dx.doi.org/10.1371/journal.ppat.1004914