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Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin

The anterior-posterior patterning of the vertebrate limb bud requires closely coordinated signaling interactions, including Sonic Hedgehog (Shh)-mediated counteraction of the Gli3 transcription factor in the distal and posterior mesenchyme of the limb bud. Suppressor of Fused (Sufu), an intracellula...

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Detalles Bibliográficos
Autores principales: Li, Jianying, Wang, Qihui, Cui, Ying, Yang, Xueqin, Li, Yan, Zhang, Xiaoyun, Qiu, Mengsheng, Zhang, Ze, Zhang, Zunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441507/
https://www.ncbi.nlm.nih.gov/pubmed/26001200
http://dx.doi.org/10.1371/journal.pone.0128006