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Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin
The anterior-posterior patterning of the vertebrate limb bud requires closely coordinated signaling interactions, including Sonic Hedgehog (Shh)-mediated counteraction of the Gli3 transcription factor in the distal and posterior mesenchyme of the limb bud. Suppressor of Fused (Sufu), an intracellula...
Autores principales: | Li, Jianying, Wang, Qihui, Cui, Ying, Yang, Xueqin, Li, Yan, Zhang, Xiaoyun, Qiu, Mengsheng, Zhang, Ze, Zhang, Zunyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441507/ https://www.ncbi.nlm.nih.gov/pubmed/26001200 http://dx.doi.org/10.1371/journal.pone.0128006 |
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