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Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer
PURPOSE: The combination of an mTOR inhibitor with 5-fluorouracil-based anticancer therapy is attractive because of preclinical evidence of synergy between these drugs. According to our phase I study, the combination of capecitabine and everolimus is safe and feasible, with potential activity in pan...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441736/ https://www.ncbi.nlm.nih.gov/pubmed/25822310 http://dx.doi.org/10.1007/s00280-015-2730-y |