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Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation

Listeria monocytogenes enters nonphagocytic cells by a receptor-mediated mechanism that is dependent on a clathrin-based molecular machinery and actin rearrangements. Bacterial intra- and intercellular movements are also actin dependent and rely on the actin nucleating Arp2/3 complex, which is activ...

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Detalles Bibliográficos
Autores principales: Kühbacher, Andreas, Emmenlauer, Mario, Rämo, Pauli, Kafai, Natasha, Dehio, Christoph, Cossart, Pascale, Pizarro-Cerdá, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442140/
https://www.ncbi.nlm.nih.gov/pubmed/25991686
http://dx.doi.org/10.1128/mBio.00598-15