Cargando…

Assessing long-distance RNA sequence connectivity via RNA-templated DNA–DNA ligation

Many RNAs, including pre-mRNAs and long non-coding RNAs, can be thousands of nucleotides long and undergo complex post-transcriptional processing. Multiple sites of alternative splicing within a single gene exponentially increase the number of possible spliced isoforms, with most human genes current...

Descripción completa

Detalles Bibliográficos
Autores principales: Roy, Christian K, Olson, Sara, Graveley, Brenton R, Zamore, Phillip D, Moore, Melissa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442144/
https://www.ncbi.nlm.nih.gov/pubmed/25866926
http://dx.doi.org/10.7554/eLife.03700