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Hepatitis C Virus Attenuates Mitochondrial Lipid β-Oxidation by Downregulating Mitochondrial Trifunctional-Protein Expression

The course of hepatitis C virus (HCV) infection and disease progression involves alterations in lipid metabolism, leading to symptoms such as hypocholesterolemia and steatosis. Steatosis can be induced by multiple mechanisms, including increases in lipid biosynthesis and uptake, impaired lipoprotein...

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Detalles Bibliográficos
Autores principales: Amako, Yutaka, Munakata, Tsubasa, Kohara, Michinori, Siddiqui, Aleem, Peers, Chris, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442397/
https://www.ncbi.nlm.nih.gov/pubmed/25673715
http://dx.doi.org/10.1128/JVI.01653-14