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Hepatitis C Virus Attenuates Mitochondrial Lipid β-Oxidation by Downregulating Mitochondrial Trifunctional-Protein Expression
The course of hepatitis C virus (HCV) infection and disease progression involves alterations in lipid metabolism, leading to symptoms such as hypocholesterolemia and steatosis. Steatosis can be induced by multiple mechanisms, including increases in lipid biosynthesis and uptake, impaired lipoprotein...
Autores principales: | Amako, Yutaka, Munakata, Tsubasa, Kohara, Michinori, Siddiqui, Aleem, Peers, Chris, Harris, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442397/ https://www.ncbi.nlm.nih.gov/pubmed/25673715 http://dx.doi.org/10.1128/JVI.01653-14 |
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