Incorporation of Peptides Targeting EGFR and FGFR1 into the Adenoviral Fiber Knob Domain and Their Evaluation as Targeted Cancer Therapies

Oncolytic virotherapies based on adenovirus 5 (Ad5) hold promise as adjunctive cancer therapies; however, their efficacy when delivered systemically is hampered by poor target cell specificity and preexisting anti-Ad5 immunity. Ovarian cancer represents a promising target for virotherapy, since the...

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Detalles Bibliográficos
Autores principales: Uusi-Kerttula, Hanni, Legut, Mateusz, Davies, James, Jones, Rachel, Hudson, Emma, Hanna, Louise, Stanton, Richard J., Chester, John D., Parker, Alan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442602/
https://www.ncbi.nlm.nih.gov/pubmed/25919378
http://dx.doi.org/10.1089/hum.2015.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442602/
https://www.ncbi.nlm.nih.gov/pubmed/25919378
http://dx.doi.org/10.1089/hum.2015.015

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