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Premalignant alterations in breast and endometrium associated with a PTEN mutation in a woman with Cowden syndrome: implications for preventive care()
• This case report documents the in vivo process of malignant transformation in a patient with Cowden syndrome. • PTEN-driven oncogenesis may proceed through a stage of pre-invasive intra-epithelial neoplasm. • Our findings have important implications for preventive care and for pathologic sampling...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442651/ https://www.ncbi.nlm.nih.gov/pubmed/26076150 http://dx.doi.org/10.1016/j.gore.2015.01.008 |