Premalignant alterations in breast and endometrium associated with a PTEN mutation in a woman with Cowden syndrome: implications for preventive care()

• This case report documents the in vivo process of malignant transformation in a patient with Cowden syndrome. • PTEN-driven oncogenesis may proceed through a stage of pre-invasive intra-epithelial neoplasm. • Our findings have important implications for preventive care and for pathologic sampling...

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Detalles Bibliográficos
Autores principales: Morse, Christopher B., Garcia, Rochelle L., Calhoun, Kristine E., Swisher, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442651/
https://www.ncbi.nlm.nih.gov/pubmed/26076150
http://dx.doi.org/10.1016/j.gore.2015.01.008

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