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Molecular basis for differential modulation of BK channel voltage-dependent gating by auxiliary γ subunits

Large conductance Ca(2+)- and voltage-activated potassium (BK) channels are comprised of pore-forming α subunits and various regulatory auxiliary subunits. The BK channel auxiliary γ (BKγ) subunits are a newly identified class of proteins containing an extracellular leucine-rich repeat domain (LRRD)...

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Detalles Bibliográficos
Autores principales: Li, Qin, Fan, Fei, Kwak, Ha Rim, Yan, Jiusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442785/
https://www.ncbi.nlm.nih.gov/pubmed/26009545
http://dx.doi.org/10.1085/jgp.201511356