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Dynamic phospholipid interaction of β2e subunit regulates the gating of voltage-gated Ca(2+) channels
High voltage-activated Ca(2+) (Ca(V)) channels are protein complexes containing pore-forming α1 and auxiliary β and α2δ subunits. The subcellular localization and membrane interactions of the β subunits play a crucial role in regulating Ca(V) channel inactivation and its lipid sensitivity. Here, we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442786/ https://www.ncbi.nlm.nih.gov/pubmed/25964431 http://dx.doi.org/10.1085/jgp.201411349 |