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Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans

The conserved Bub1/Bub3 complex is recruited to the kinetochore region of mitotic chromosomes, where it initiates spindle checkpoint signaling and promotes chromosome alignment. Here we show that, in contrast to the expectation for a checkpoint pathway component, the BUB-1/BUB-3 complex promotes tim...

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Detalles Bibliográficos
Autores principales: Kim, Taekyung, Moyle, Mark W., Lara-Gonzalez, Pablo, De Groot, Christian, Oegema, Karen, Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442812/
https://www.ncbi.nlm.nih.gov/pubmed/25987605
http://dx.doi.org/10.1083/jcb.201412035