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Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
The conserved Bub1/Bub3 complex is recruited to the kinetochore region of mitotic chromosomes, where it initiates spindle checkpoint signaling and promotes chromosome alignment. Here we show that, in contrast to the expectation for a checkpoint pathway component, the BUB-1/BUB-3 complex promotes tim...
Autores principales: | Kim, Taekyung, Moyle, Mark W., Lara-Gonzalez, Pablo, De Groot, Christian, Oegema, Karen, Desai, Arshad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442812/ https://www.ncbi.nlm.nih.gov/pubmed/25987605 http://dx.doi.org/10.1083/jcb.201412035 |
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