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3′,4′,5′,5,7-Pentamethoxyflavone Sensitizes Cisplatin-Resistant A549 Cells to Cisplatin by Inhibition of Nrf2 Pathway

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important redox-sensitive transcription factor that regulates the expression of several cytoprotective genes. More recently, genetic analyses of human tumors have indicated that Nrf2 may cause resistance to chemotherapy. In this study, we foun...

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Detalles Bibliográficos
Autores principales: Hou, Xiangyu, Bai, Xupeng, Gou, Xiaoli, Zeng, Hang, Xia, Chen, Zhuang, Wei, Chen, Xinmeng, Zhao, Zhongxiang, Huang, Min, Jin, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443280/
https://www.ncbi.nlm.nih.gov/pubmed/25843086
http://dx.doi.org/10.14348/molcells.2015.2183