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N-Acetyl-D-Glucosamine Kinase Is a Component of Nuclear Speckles and Paraspeckles

Protein O-GlcNAcylation, dictated by cellular UDP-N-acetylglucosamine (UDP-GlcNAc) levels, plays a crucial role in posttranslational modifications. The enzyme GlcNAc kinase (NAGK, E.C. 2.7.1.59) catalyzes the formation of GlcNAc-6-phosphate, which is a major substrate for the biosynthesis of UDP-Glc...

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Detalles Bibliográficos
Autores principales: Sharif, Syeda Ridita, Lee, HyunSook, Islam, Md. Ariful, Seog, Dae-Hyun, Moon, Il Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443281/
https://www.ncbi.nlm.nih.gov/pubmed/25921606
http://dx.doi.org/10.14348/molcells.2015.2242