STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells

Recognition of cytosolic DNA initiates a series of innate immune responses by inducing IFN-I production and subsequent triggering JAK1-STAT1 signaling which plays critical roles in the pathogenesis of infection, inflammation and autoimmune diseases through promoting B cell activation and antibody re...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Guanjun, You, Ming, Ding, Liang, Fan, Hongye, Liu, Fei, Ren, Deshan, Hou, Yayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443286/
https://www.ncbi.nlm.nih.gov/pubmed/25947293
http://dx.doi.org/10.14348/molcells.2015.2359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443286/
https://www.ncbi.nlm.nih.gov/pubmed/25947293
http://dx.doi.org/10.14348/molcells.2015.2359

Ejemplares similares