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STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells

Recognition of cytosolic DNA initiates a series of innate immune responses by inducing IFN-I production and subsequent triggering JAK1-STAT1 signaling which plays critical roles in the pathogenesis of infection, inflammation and autoimmune diseases through promoting B cell activation and antibody re...

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Detalles Bibliográficos
Autores principales:	Dong, Guanjun, You, Ming, Ding, Liang, Fan, Hongye, Liu, Fei, Ren, Deshan, Hou, Yayi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443286/ https://www.ncbi.nlm.nih.gov/pubmed/25947293 http://dx.doi.org/10.14348/molcells.2015.2359

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