Cargando…

Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells

The 15-kDa selenoprotein (Sep15) is a selenoprotein residing in the lumen of the endoplasmic reticulum (ER) and implicated in quality control of protein folding. Herein, we established an inducible RNAi cell line that targets Sep15 mRNA in Chang liver cells. RNAi-induced Sep15 deficiency led to inhi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bang, Jeyoung, Huh, Jang Hoe, Na, Ji-Woon, Lu, Qiao, Carlson, Bradley A., Tobe, Ryuta, Tsuji, Petra A., Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443288/
https://www.ncbi.nlm.nih.gov/pubmed/25728752
http://dx.doi.org/10.14348/molcells.2015.0007