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Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells
The 15-kDa selenoprotein (Sep15) is a selenoprotein residing in the lumen of the endoplasmic reticulum (ER) and implicated in quality control of protein folding. Herein, we established an inducible RNAi cell line that targets Sep15 mRNA in Chang liver cells. RNAi-induced Sep15 deficiency led to inhi...
Autores principales: | Bang, Jeyoung, Huh, Jang Hoe, Na, Ji-Woon, Lu, Qiao, Carlson, Bradley A., Tobe, Ryuta, Tsuji, Petra A., Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443288/ https://www.ncbi.nlm.nih.gov/pubmed/25728752 http://dx.doi.org/10.14348/molcells.2015.0007 |
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