Cargando…

Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells

The 15-kDa selenoprotein (Sep15) is a selenoprotein residing in the lumen of the endoplasmic reticulum (ER) and implicated in quality control of protein folding. Herein, we established an inducible RNAi cell line that targets Sep15 mRNA in Chang liver cells. RNAi-induced Sep15 deficiency led to inhi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bang, Jeyoung, Huh, Jang Hoe, Na, Ji-Woon, Lu, Qiao, Carlson, Bradley A., Tobe, Ryuta, Tsuji, Petra A., Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443288/ https://www.ncbi.nlm.nih.gov/pubmed/25728752 http://dx.doi.org/10.14348/molcells.2015.0007

Ejemplares similares

Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice
por: Tsuji, Petra A., et al.
Publicado: (2012)

The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways
por: Tsuji, Petra A., et al.
Publicado: (2015)

Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity
por: Canter, Jessica A., et al.
Publicado: (2021)

Deficiency in the 15 kDa Selenoprotein Inhibits Human Colon Cancer Cell Growth
por: Tsuji, Petra A., et al.
Publicado: (2011)

Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly
por: Tsuji, Petra A., et al.
Publicado: (2021)

Mouse Models Targeting Selenocysteine tRNA Expression for Elucidating the Role of Selenoproteins in Health and Development
por: Carlson, Bradley A., et al.
Publicado: (2009)

Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy
por: Tobe, Ryuta, et al.
Publicado: (2015)

UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins
por: Turanov, Anton A., et al.
Publicado: (2013)

Selenoproteins Are Essential for Proper Keratinocyte Function and Skin Development
por: Sengupta, Aniruddha, et al.
Publicado: (2010)

Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression
por: Carlson, Bradley A, et al.
Publicado: (2009)

DnaJB6: an indirect interaction protein of 15-kDa selenoprotein
por: Tian, Jing, et al.
Publicado: (2012)

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration
por: Carlson, Bradley A., et al.
Publicado: (2016)

Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine
por: Turanov, Anton A., et al.
Publicado: (2015)

Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice
por: Tsuji, Petra A., et al.
Publicado: (2015)

Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1(−/−) Mice
por: Bang, Jeyoung, et al.
Publicado: (2021)

Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery
por: Santesmasses, Didac, et al.
Publicado: (2021)

Cerebellar Hypoplasia in Mice Lacking Selenoprotein Biosynthesis in Neurons
por: Wirth, Eva K., et al.
Publicado: (2014)

Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-α-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus
por: Yoo, Min-Hyuk, et al.
Publicado: (2013)

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
por: Ouali, Boimpoundi Eunice Flavie, et al.
Publicado: (2020)

HIF-Independent Regulation of Thioredoxin Reductase 1 Contributes to the High Levels of Reactive Oxygen Species Induced by Hypoxia
por: Naranjo-Suarez, Salvador, et al.
Publicado: (2012)

Reduced reliance on the trace element selenium during evolution of mammals
por: Lobanov, Alexey V, et al.
Publicado: (2008)

Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFα
por: Moustafa, Mohamed E., et al.
Publicado: (2013)

Adaptive Thermogenesis in a Mouse Model Lacking Selenoprotein Biosynthesis in Brown Adipocytes
por: Seale, Lucia A., et al.
Publicado: (2021)

SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes
por: Mix, Heiko, et al.
Publicado: (2007)

Data on physicochemical properties of LPEI 25 kDa, PEI“Max” 40 kDa and PEIpro™
por: Delafosse, Laurence, et al.
Publicado: (2016)

Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication
por: Yoo, Min-Hyuk, et al.
Publicado: (2007)

In silico identification of genes involved in selenium metabolism: evidence for a third selenium utilization trait
por: Zhang, Yan, et al.
Publicado: (2008)

In Vitro Inhibition of Angiogenesis by Antibodies Directed against the 37kDa/67kDa Laminin Receptor
por: Khusal, Raksha, et al.
Publicado: (2013)

SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins
por: Mariotti, Marco, et al.
Publicado: (2013)

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura
por: Xiao, Chengfeng, et al.
Publicado: (2004)

Selenium metabolism in Trypanosoma: characterization of selenoproteomes and identification of a Kinetoplastida-specific selenoprotein
por: Lobanov, Alexey V., et al.
Publicado: (2006)

The 37kDa/67kDa Laminin Receptor acts as a receptor for Aβ(42) internalization
por: Da Costa Dias, Bianca, et al.
Publicado: (2014)

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity
por: Naidoo, Kerrilyn, et al.
Publicado: (2015)

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)
por: Mahdi, Yassin, et al.
Publicado: (2015)

SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements
por: Castellano, Sergi, et al.
Publicado: (2008)

Enhanced gene transfection efficiency by low-dose 25 kDa polyethylenimine by the assistance of 1.8 kDa polyethylenimine
por: Zhang, Hui, et al.
Publicado: (2018)

Hydrogen Peroxide Probes Directed to Different Cellular Compartments
por: Malinouski, Mikalai, et al.
Publicado: (2011)

Characterization of Mammalian Selenoprotein O: A Redox-Active Mitochondrial Protein
por: Han, Seong-Jeong, et al.
Publicado: (2014)

Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction
por: Jung, Jisu, et al.
Publicado: (2021)

Comprehensive Enzymatic Analysis of the Cellulolytic System in Digestive Fluid of the Sea Hare Aplysia kurodai. Efficient Glucose Release from Sea Lettuce by Synergistic Action of 45 kDa Endoglucanase and 210 kDa ß-Glucosidase
por: Tsuji, Akihiko, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hanklc8vj1fppt70ovup9572vh