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Brain-derived neurotrophic factor is required for axonal growth of selective groups of neurons in the arcuate nucleus
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development, and the Bdnf gene produces two populations of transcripts with either a short or long 3′ untranslated region (3′ UTR). Deficiencies in BDNF signaling have been shown to cause severe obesity in humans;...
Autores principales: | Liao, Guey-Ying, Bouyer, Karine, Kamitakahara, Anna, Sahibzada, Niaz, Wang, Chien-Hua, Rutlin, Michael, Simerly, Richard B., Xu, Baoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443292/ https://www.ncbi.nlm.nih.gov/pubmed/26042201 http://dx.doi.org/10.1016/j.molmet.2015.03.003 |
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