Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis

OBJECTIVES: Salubrinal is a synthetic agent that elevates phosphorylation of eukaryotic translation initiation factor 2 alpha (eIF2α) and alleviates stress to the endoplasmic reticulum. Previously, we reported that in chondrocytes, Salubrinal attenuates expression and activity of matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Hamamura, K., Nishimura, A., Iino, T., Takigawa, S., Sudo, A., Yokota, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Editorial Society of Bone and Joint Surgery 2015
Materias:
General Orthopaedics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443296/
https://www.ncbi.nlm.nih.gov/pubmed/25977571
http://dx.doi.org/10.1302/2046-3758.45.2000378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443296/
https://www.ncbi.nlm.nih.gov/pubmed/25977571
http://dx.doi.org/10.1302/2046-3758.45.2000378

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