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Evaluation of In Vivo Transfection Efficiency of Eudragit Coated Nanoparticles of Chitosan-DNA: A pH-sensitive System Prepared for Oral DNA Delivery

BACKGROUND: Success of any gene therapy protocol relies mostly on using an efficient carrier to direct nucleic acid to the place of action. The system should also have transfection ability at release site. Different routes are available for delivering genetic materials to the target organs, amongst...

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Detalles Bibliográficos
Autores principales: Momenzadeh, Sedigheh, Sadeghi, Abdorrahim, Vatandoust, Nasimeh, Salehi, Rasoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443396/
https://www.ncbi.nlm.nih.gov/pubmed/26023332
http://dx.doi.org/10.5812/ircmj.17(4)2015.16761