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Most partial domains in proteins are alignment and annotation artifacts
BACKGROUND: Protein domains are commonly used to assess the functional roles and evolutionary relationships of proteins and protein families. Here, we use the Pfam protein family database to examine a set of candidate partial domains. Pfam protein domains are often thought of as evolutionarily indiv...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443539/ https://www.ncbi.nlm.nih.gov/pubmed/25976240 http://dx.doi.org/10.1186/s13059-015-0656-7 |