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Domain similarity based orthology detection

BACKGROUND: Orthologous protein detection software mostly uses pairwise comparisons of amino-acid sequences to assert whether two proteins are orthologous or not. Accordingly, when the number of sequences for comparison increases, the number of comparisons to compute grows in a quadratic order. A cu...

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Detalles Bibliográficos
Autores principales: Bitard-Feildel, Tristan, Kemena, Carsten, Greenwood, Jenny M, Bornberg-Bauer, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443542/
https://www.ncbi.nlm.nih.gov/pubmed/25968113
http://dx.doi.org/10.1186/s12859-015-0570-8