Predictions for optimal mitigation of paracrine inhibitory signalling in haemopoietic stem cell cultures

INTRODUCTION: Recent studies in the literature have highlighted the critical role played by cell signalling in determining haemopoietic stem cell (HSC) fate within ex vivo culture systems. Stimulatory signals can enhance proliferation and promote differentiation, whilst inhibitory signals can signif...

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Detalles Bibliográficos
Autores principales: Berry, Joseph D, Godara, Pankaj, Liovic, Petar, Haylock, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443622/
https://www.ncbi.nlm.nih.gov/pubmed/25888759
http://dx.doi.org/10.1186/s13287-015-0048-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443622/
https://www.ncbi.nlm.nih.gov/pubmed/25888759
http://dx.doi.org/10.1186/s13287-015-0048-7

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