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Predictions for optimal mitigation of paracrine inhibitory signalling in haemopoietic stem cell cultures
INTRODUCTION: Recent studies in the literature have highlighted the critical role played by cell signalling in determining haemopoietic stem cell (HSC) fate within ex vivo culture systems. Stimulatory signals can enhance proliferation and promote differentiation, whilst inhibitory signals can signif...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443622/ https://www.ncbi.nlm.nih.gov/pubmed/25888759 http://dx.doi.org/10.1186/s13287-015-0048-7 |