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Overexpression of P21-activated kinase 4 is associated with poor prognosis in non-small cell lung cancer and promotes migration and invasion

BACKGROUND: P21-activated kinase 4 (PAK4), an effector of the Rho family protein Cdc42, is an important oncogene whose expression is increased in many human cancers and is generally positively correlated with advanced disease and decreased survival. However, little is known about the expression and...

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Detalles Bibliográficos
Autores principales: Cai, Songwang, Ye, Zhiqiang, Wang, Xiaohong, Pan, Yuhang, Weng, Yimin, Lao, Sen, Wei, Hongbo, Li, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443662/
https://www.ncbi.nlm.nih.gov/pubmed/25975262
http://dx.doi.org/10.1186/s13046-015-0165-2