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Overexpression of P21-activated kinase 4 is associated with poor prognosis in non-small cell lung cancer and promotes migration and invasion
BACKGROUND: P21-activated kinase 4 (PAK4), an effector of the Rho family protein Cdc42, is an important oncogene whose expression is increased in many human cancers and is generally positively correlated with advanced disease and decreased survival. However, little is known about the expression and...
Autores principales: | Cai, Songwang, Ye, Zhiqiang, Wang, Xiaohong, Pan, Yuhang, Weng, Yimin, Lao, Sen, Wei, Hongbo, Li, Lian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443662/ https://www.ncbi.nlm.nih.gov/pubmed/25975262 http://dx.doi.org/10.1186/s13046-015-0165-2 |
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