Mutation signatures implicate aristolochic acid in bladder cancer development

BACKGROUND: Aristolochic acid (AA) is a natural compound found in many plants of the Aristolochia genus, and these plants are widely used in traditional medicines for numerous conditions and for weight loss. Previous work has connected AA-mutagenesis to upper-tract urothelial cell carcinomas and hep...

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Detalles Bibliográficos
Autores principales: Poon, Song Ling, Huang, Mi Ni, Choo, Yang, McPherson, John R, Yu, Willie, Heng, Hong Lee, Gan, Anna, Myint, Swe Swe, Siew, Ee Yan, Ler, Lian Dee, Ng, Lay Guat, Weng, Wen-Hui, Chuang, Cheng-Keng, Yuen, John SP, Pang, See-Tong, Tan, Patrick, Teh, Bin Tean, Rozen, Steven G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443665/
https://www.ncbi.nlm.nih.gov/pubmed/26015808
http://dx.doi.org/10.1186/s13073-015-0161-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443665/
https://www.ncbi.nlm.nih.gov/pubmed/26015808
http://dx.doi.org/10.1186/s13073-015-0161-3

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