TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples

Summary: Network pharmacology-based prediction of multi-targeted drug combinations is becoming a promising strategy to improve anticancer efficacy and safety. We developed a logic-based network algorithm, called Target Inhibition Interaction using Maximization and Minimization Averaging (TIMMA), whi...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Liye, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443685/
https://www.ncbi.nlm.nih.gov/pubmed/25638808
http://dx.doi.org/10.1093/bioinformatics/btv067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443685/
https://www.ncbi.nlm.nih.gov/pubmed/25638808
http://dx.doi.org/10.1093/bioinformatics/btv067

Ejemplares similares